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Nov 08, 2008

Label-Free Pathogen Detection with Sensor Chips Assembled from Peptide Nanotubes

Laura Lechuga, leader of the Nanobiosensors and Molecular Nanobiophysics, together with other researchers, published the paper 'Label-Free Pathogen Detection with Sensor Chips Assembled from Peptide Nanotubes' on Angewandte Chemie, Volume 120, Issue 50, Pages 9898-9901.

Advances in bottom-up nanofabrication have led to the use of various nanomaterials with superior physical properties as building blocks for the assembly of devices with complex configurations. Peptide nanotubes are useful nanomaterial building blocks that have been used to construct a variety of device geometries, as their self-assembly is robust, and locations for their immobilization on substrates can be targeted by biomolecular recognition.[12, 13] However, one of the unexplored areas in devices based on peptide nanotubes is the lab-on-chip sensor. Herein, we examine the feasibility of assembling peptide-nanotube sensors with a simple chip geometry for the electrical detection of viruses with an extremely low detection limit.

Label-Free Pathogen Detection with Sensor Chips Assembled from Peptide Nanotubes

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