Research activities

Our Group focus its activities inside the Nanobiotechnology area and is involved in the development of nanobiosensors devices, biofunctionalization of inorganic surfaces and nanostructures and applications of the nanodevices in clinical diagnostics, environmental control, genomics and proteomics.

The research activities range from the basic research to the technological implementations of nanodevices, following the way to the industrial transfer of our research into products. The nanobiosensors are applied for the early detection of cancer, the detection of toxic environmental pollutants, the early detection and treatment of infectious agents and the detection of hormone disorders, among others.

The following biosensors are developed in the group:

  • Integrated Mach-Zehnder Interferometer devices and its integration with polymer microfluidics
  • A novel Interferometric bimodal waveguide sensor
  • A portable Surface Plasmon Resonance Biosensor
  • A novel Magnetooptical Surface Plasmon Resonance Biosensor
  • Plasmonic Nanobiosensors based on nanostructures
  • Nanomechanical biosensors based on Silicon microcantilevers
  • A novel nanomechanical biosensor based on waveguided microcantilevers

The main research activities of the Biosensors and Bioanalytical Applications Group are:

1) the development of nanobiosensor devices; biofunctionalization of surfaces; and integration in lab-on-a-chip microsystems.

2) the application of the devices in relevant  diagnostic problems as early detection of pathogens, cancer and other diseases in real  biological samples.

Description of the research activities:

Plasmonics Biosensors

We have developed a portable SPR platform, currently commercialised by our spin-off company SENSIA, SL.

We have introduced a new plasmonic biosensor based on Magnetooptical effects (MOSPR).

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Nanoplasmonics Biosensors

The aim of this research line is the development of highly sensitive multiplexed biosensing platforms based on the Localized Surface Plasmon Resonance (LSPR) of metal nanostructures.  

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Integrated Nanophotonics Biosensors

 

We develop integrated nanointerferometers devices for biosensors of high performance. They combine at the same time high sensitivity, mechanical stability, miniaturisation and the possibility of mass-production.

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Nanomechanical biosensors

We work on the development of nanomechanical biosensor arrays based on standard microcantilevers and on microcantilevers acting as optical waveguides.

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Biofunctionalization of nanobiosensor surfaces

We develop different immobilization strategies at the nanometer scale for the biological receptors anchorage to the biosensor surface in order to achieve robust and reproducible devices of high performance. We work with gold, silicon and glass surfaces.

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Lab-on-a-chip platforms

The final goal is the integration of the biosensor devices in lab-on-a-chip platforms which could be used as a hand-held and portable device for clinical diagnosis of relevant analytes (point-of-care diagnostic tool)

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Biosensors Group 2012, CIN2, CSIC, Spain | Site map | About this site | Site by Gros.es